Chemotherapy Treatment Guides

Plain-language guides for caregivers and patients — what to expect each day of your cycle, which symptoms to watch for, and when to call the care team.

FOLFOX

Folinic Acid, Fluorouracil, and Oxaliplatin

severe effects
colorectal cancercolon cancer+1 more

FOLFOX is one of the most common chemotherapy regimens for colorectal cancer. It combines three drugs given over 2 days every 2 weeks.

14-day cycle12 typical cycles6 tracked side effects

FOLFIRI

Folinic Acid, Fluorouracil, and Irinotecan

severe effects
colorectal cancercolon cancer+2 more

FOLFIRI is a colorectal cancer chemotherapy regimen that replaces oxaliplatin with irinotecan. Often used after FOLFOX or when neuropathy is a concern.

14-day cycle12 typical cycles6 tracked side effects

FOLFIRINOX

Folinic Acid, Fluorouracil, Irinotecan, and Oxaliplatin

severe effects
pancreatic cancercolorectal cancer

FOLFIRINOX is an aggressive four-drug regimen used for pancreatic cancer and some colorectal cancers. It is highly effective but has significant side effects.

14-day cycle12 typical cycles6 tracked side effects

ABVD

Adriamycin, Bleomycin, Vinblastine, and Dacarbazine

severe effects
Hodgkin lymphoma

ABVD is the standard treatment for Hodgkin lymphoma. Four drugs are given on days 1 and 15 of each 28-day cycle.

28-day cycle6 typical cycles6 tracked side effects

R-CHOP

Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone

severe effects
diffuse large B-cell lymphomafollicular lymphoma+1 more

R-CHOP is the standard treatment for B-cell non-Hodgkin lymphomas. Six drugs (including a targeted therapy) are given every 3 weeks.

21-day cycle6 typical cycles6 tracked side effects

AC-T

Adriamycin, Cyclophosphamide, followed by Taxol (Paclitaxel)

severe effects
breast cancer

AC-T (dose-dense) is a common breast cancer regimen. Four cycles of AC are given every 2 weeks, followed by four cycles of Taxol every 2 weeks.

14-day cycle8 typical cycles6 tracked side effects

Carbo-Taxol

Carboplatin and Paclitaxel (Taxol)

severe effects
ovarian cancerlung cancer+2 more

Carboplatin + Paclitaxel is a widely used regimen across several cancer types. Given every 3 weeks for 6 cycles.

21-day cycle6 typical cycles6 tracked side effects

Gem-Cis

Gemcitabine and Cisplatin

severe effects
bladder cancerlung cancer+2 more

Gemcitabine + Cisplatin is used for bladder, lung, and other cancers. Given over 3 weeks with a rest week.

21-day cycle6 typical cycles5 tracked side effects

BEACOPP

Bleomycin, Etoposide, Adriamycin, Cyclophosphamide, Vincristine, Procarbazine, and Prednisone

severe effects
Hodgkin lymphoma (advanced stage)

Escalated BEACOPP is used for advanced Hodgkin lymphoma when ABVD is insufficient. It is more intensive with a higher side effect burden.

21-day cycle6 typical cycles6 tracked side effects

CMF

Cyclophosphamide, Methotrexate, and Fluorouracil

moderate effects
breast cancer

CMF is an older breast cancer regimen still used in some settings. Less intense than AC-T but still effective for certain patients.

28-day cycle6 typical cycles5 tracked side effects

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